Archive for December, 2009

FAK Mediates the Activation of Cardiac Fibroblasts Induced by Mechanical Stress Through Regulation of the mTOR Complex.

Thursday, December 31st, 2009

Related Articles FAK Mediates the Activation of Cardiac Fibroblasts Induced by Mechanical Stress Through Regulation of the mTOR Complex. Cardiovasc Res. 2009 Dec 28; Authors: Costa AP, Clemente ...

Map4k4 negatively regulates PPAR{gamma} protein translation by suppressing the mTOR signaling pathway in cultured adipocytes.

Thursday, December 31st, 2009

Related Articles Map4k4 negatively regulates PPAR{gamma} protein translation by suppressing the mTOR signaling pathway in cultured adipocytes. J Biol Chem. 2009 Dec 28; Authors: Guntur KV, Guilherme A, ...

mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes.

Thursday, December 31st, 2009

Related Articles mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes. Cell Cycle. 2010 Feb 7;9(5) Authors: Tsang CK, Liu H, Zheng XF ...

New Source Of Classical Techniques For Blood-Based Studies In The Laboratory Mouse

Thursday, December 31st, 2009

The mouse is a standard laboratory model organism, but there are currently few resources that describe conventional techniques to analyze blood and blood-forming tissues in this species. A newly released set of compact and easy-to-use laboratory resources from Cold Spring Harbor Laboratory Press fills this gap...

Marking Of Tissue-Specific Crucial In Embryonic Stem Cells To Ensure Proper Function

Thursday, December 31st, 2009

Tissue-specific genes, thought to be dormant or not marked for activation in embryonic stem cells, are indeed marked by transcription factors, with proper marking potentially crucial for the function of tissues derived from stem cells...

Lack Of Diversity In Embryonic Stem Cell Lines Revealed By U-M Study

Thursday, December 31st, 2009

The most widely used human embryonic stem cell lines lack genetic diversity, a finding that raises social justice questions that must be addressed to ensure that all sectors of society benefit from stem cell advances, according to a University of Michigan research team...

Stem-Cell Activators Switch Function, Repress Mature Cells

Thursday, December 31st, 2009

In a developing animal, stem cells proliferate and differentiate to form the organs needed for life. A new study shows how a crucial step in this process happens and how a reversal of that step contributes to cancer. The study, led by researchers at the Ohio State University Comprehensive Cancer ...

Umbilical Cord Could Be New Source Of Plentiful Stem Cells, Say Pitt Researchers

Thursday, December 31st, 2009

Stem cells that could one day provide therapeutic options for muscle and bone disorders can be easily harvested from the tissue of the umbilical cord, just as the blood that goes through it provides precursor cells to treat some blood disorders, said University of Pittsburgh School of Medicine researchers in ...

Neuralstem Receives Approval To Commence First ALS Stem Cell Trial At Emory ALS Center

Thursday, December 31st, 2009

Neuralstem, Inc. (NYSE Amex: CUR) announced that its Phase I trial to treat Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's disease) with its spinal cord stem cells has been approved by the Institutional Review Board (IRB) at Emory University in Atlanta, GA. The trial, which was approved by the FDA ...

Editorial Criticizes Mich. Lawmakers’ Attempts To Restrict Stem Cell Research Using Donated Embryo

Thursday, December 31st, 2009

"A year after Michigan voters approved the broader use of donated embryos for stem cell research, some state legislators are seeking to put limits on the science," a Detroit News editorial says...

Bioheart Makes Breakthrough In Critical Limb Ischemia Therapy With Stem Cells Obtained From Fat Tissue

Thursday, December 31st, 2009

Bioheart, Inc. (OTC Bulletin Board: BHRT) offers yet another medical breakthrough with the next-level stem cell treatment for critical limb ischemia patients. The stem cells aid in promoting angiogenesis or the formation of new blood vessels and providing support for the healing of damaged blood vessels...

$1.4 Million Grant Received By Boston University School Of Medicine

Thursday, December 31st, 2009

Boston University School of Medicine's (BUSM) Pulmonary Center has received a two-year $1.4 million grant from the National Heart, Lung, and Blood Institute to derive stem cells and lung progenitors from patients with lung disease...

School Of Medicine Receives $30 Million Grant To Coordinate A Consortium Of National Stem Cell Experts

Thursday, December 31st, 2009

A University of Maryland School of Medicine researcher will lead the coordinating center for a consortium of our nation's most prominent scientists in the field of stem cell research. Michael L. Terrin, M.D.,C.M.,M.P.H...

Chemotherapy-induced heart damage reversed in rats

Thursday, December 31st, 2009

Source: American Heart AssociationDate: December 28, 2009Summary: DALLAS, — Heart tissue damage from chemotherapy drugs was reversed in rats by using their own cardiac stem cells (CSCs) that weren’t exposed to the cancer treatment. These cells reversed heart failure, according to a new study in Circulation: Journal of the ...

Scripps research team develops technique to determine ethnic origin of stem cell lines

Thursday, December 31st, 2009

Source: Scripps Research InstituteDate: December 29, 2009Summary:An international team of scientists led by researchers at The Scripps Research Institute has developed a straightforward technique to determine the ethnic origin of stem cells. The Scripps Research scientists initiated the study—published in the January 2010 edition of the prestigious journal Nature ...

Scientists develop technique to determine ethnic origin of stem cell lines

Thursday, December 31st, 2009

Scientists have developed a straightforward technique to determine the ethnic origin of stem cells. The team's analysis of a variety of human embryonic stem cell lines currently in use in research laboratories around the world found that these cells originated largely from Caucasian and East Asian populations, with little representation ...

Lec 8 | MIT 7.014 Introductory Biology, Spring 2005

Wednesday, December 30th, 2009

This shows some chromosomes that are all bunched up and are just pulled apart at the time of the cell division. Those chromosomes, as we now know, are made of DNA. But in essence what people had seen through the microscope was these chromosomes or colored things that they could ...

Cord blood – could an umbilical cord really save lives? – Horizon – Lifeblood – BBC

Wednesday, December 30th, 2009

Amazing research in to cord blood, found in baby's umbilical cords that can save lives due to the high number of stem cells it contains. Brilliant video from BBC show Life Blood. Watch more high quality videos on the Explore YouTube channel from BBC Worldwide here: www.youtube.com ... BBC Life ...

Lymphoma: Recurrence Two Years After Intensive Chemotherapy

Wednesday, December 30th, 2009

In 1997, he was diagnosed with T-cell high grade non-Hodgkin's Lymphoma Stage 1A. Fot 2 years, he was in and out of hospital undergoing chemotherapy. Despite all he endured, he suffered a relapse. He decided to opt for CA Care Therapy. He got better. Today, seven years later he remained ...

Multiple-turnover isotopic labeling of fmoc- and boc-protected amino acids with oxygen isotopes.

Wednesday, December 30th, 2009

Related Articles Multiple-turnover isotopic labeling of fmoc- and boc-protected amino acids with oxygen isotopes. Org Lett. 2010 Jan 1;12(1):104-6 Authors: Seyfried MS, Lauber BS, Luedtke NW ...