Archive for the ‘Stem Cell Transplant Clinical Trials’ Category

Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

Friday, December 18th, 2009

Conditions:   Stem Cell Transplantation;   Transplantation, Homologous;   Allogenic Stem Cell Transplant RecipientIntervention:   Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)Recruiting - verified December 2008

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Stem Cell Transplantation for Children Affected With Osteopetrosis

Friday, December 18th, 2009

Condition:   OsteopetrosisInterventions:   Procedure: Stem Cell Transplantation;   Device: Miltenyi Biotec CliniMACS;   Drug: Systemic chemotherapy and antibodiesSponsor:   St. Jude Children's Research HospitalCompleted - verified February 2009

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Stem Cell Transplantation as Immunotherapy for Hematologic Malignancies

Friday, December 18th, 2009

Conditions:   Leukemia;   Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Chronic Myeloid Leukemia;   Juvenile Myelomonocytic Leukemia;   Myelodysplastic Syndrome;   Paroxysmal Nocturnal Hemoglobinuria;   Hodgkin's Lymphoma;   Non-Hodgkin LymphomaInterventions:   Drug: Systematic chemotherapy and antibodies;   Procedure: Allogeneic stem cell transplantation;   Device: Miltenyi CliniMACSSponsor:   St. Jude Children's Research HospitalCompleted - verified January 2009

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Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies

Friday, December 18th, 2009

Conditions:   Acute Lymphoblastic Leukemia (ALL);   Acute Myeloid Leukemia (AML);   Secondary AML;   Myelodysplastic Syndrome (MDS);   Secondary MDS;   Chronic Myeloid Leukemia;   Juvenile Myelomonocytic Leukemia (JMML);   Paroxysmal Nocturnal Hemoglobinuria (PNH);   Lymphoma, Non-Hodgkin;   Hodgkin DiseaseInterventions:   Procedure: Stem Cell Transplantation;   Device: Miltenyi Biotec CliniMACS;   Drug: Systemic chemotherapy and antibodiesSponsor:   St. Jude Children's Research HospitalCompleted - verified February 2009

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Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound

Friday, December 18th, 2009

Condition:   Sickle Cell DiseaseInterventions:   Procedure: Hematopoietic Stem Cell Transplantation;   Device: CliniMACS;   Drug: See intervention descriptionSponsor:   St. Jude Children's Research HospitalCompleted - verified February 2009

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Stem Cell Transplantation for Patients With Hematologic Malignancies

Friday, December 18th, 2009

Conditions:   Acute Lymphoblastic Leukemias;   Acute Myelocytic Leukemia;   Chronic Myeloid Leukemia;   Juvenile Myelomonocytic Leukemia;   Myelodysplastic Syndrome;   Hemoglobinuria, Paroxysmal;   Non-Hodgkin LymphomaInterventions:   Procedure: Allogeneic Stem Cell Transplantation;   Drug: Chemotherapy and antibodiesSponsor:   St. Jude Children's Research HospitalCompleted - verified January 2009

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Stem Cell Transplant for Immunologic or Histiocytic Disorders

Friday, December 18th, 2009

Conditions:   Hemophagocytic Lymphohistiocytosis;   X-Linked Lymphoproliferative Disorders;   Chediak-Higashi Syndrome;   Griscelli Syndrome;   Immunologic Deficiency Syndromes;   Langerhans-Cell HistiocytosisInterventions:   Procedure: Stem Cell Transplant;   Drug: Fludarabine, melphalan, ATG or CampathSponsor:   Masonic Cancer Center, University of MinnesotaRecruiting - verified September 2009

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Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias

Friday, December 18th, 2009

Conditions:   Anemia, Aplastic;   Amegakaryocytic Thrombocytopenia;   Diamond-Blackfan Anemia;   Kostmann SyndromeIntervention:   Procedure: Allogeneic stem cell transplantSponsor:   St. Jude Children's Research HospitalCompleted - verified February 2009

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Stem Cell Transplant in Sickle Cell Disease and Thalassemia

Friday, December 18th, 2009

Conditions:   Sickle Cell Disease;   Beta ThalassemiaInterventions:   Drug: Busulfan;   Drug: Fludarabine;   Drug: Alemtuzumab;   Procedure: Allogeneic stem cell transplantSponsor:   Columbia UniversityRecruiting - verified August 2009

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Conditioning Regimen in Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation

Friday, December 18th, 2009

Condition:   Renal Cell CancerInterventions:   Drug: Fludarabine;   Drug: Melphalan;   Drug: Cyclophosphamide;   Procedure: Stem Cell TransplantSponsor:   M.D. Anderson Cancer CenterTerminated - verified August 2009

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Sm-EDTMP and Autologous Peripheral Blood Stem Cell Transplantation for Breast Cancer Patients With Bone Only Metastases

Friday, December 18th, 2009

Conditions:   Breast Cancer;   Bone MetastasesInterventions:   Drug: 153 Sm-EDTMP;   Behavioral: Questionnaire;   Procedure: Stem Cell TransplantSponsors:   M.D. Anderson Cancer Center;   Cytogen CorporationRecruiting - verified September 2009

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Abdominal Obesity and Cardiovascular Risk Factors in Women Who Survived Cancer or a Related Illness Following Total Body Irradiation and Stem Cell Transplant

Friday, December 18th, 2009

Conditions:   Leukemia;   Hodgkin's Lymphoma;   Non-Hodgkin's Lymphoma;   Myelodysplastic SyndromeIntervention:   Other: Questionnaires, Laboratory tests, Abdominal MRISponsors:   Memorial Sloan-Kettering Cancer Center;   Queen's University, Kingston, Ontario;   Weill Medical College of Cornell UniversityRecruiting - verified October 2009

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Natural Killer (NK) Cell Adback After Allogeneic Stem Cell Transplant With Campath-IH Plus Chemorx for Patients With Lymphoid Malignancies

Friday, December 18th, 2009

Conditions:   Lymphoma;   LeukemiaInterventions:   Drug: ARA-C;   Drug: BCNU;   Drug: Campath-1H;   Drug: Cyclophosphamide;   Drug: Etoposide;   Drug: Fludarabine;   Drug: Melphalan;   Drug: Rituximab;   Other: Allogeneic Stem Cell TransplantationSponsor:   M.D. Anderson Cancer CenterActive, not recruiting - verified September 2009

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Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

Friday, December 18th, 2009

Conditions:   Leukemia, Acute Lymphocytic (ALL);   Leukemia, Myeloid, Acute(AML);   Leukemia, Myeloid, Chronic(CML);   Juvenile Myelomonocytic Leukemia (JMML);   Hemoglobinuria, Paroxysmal Nocturnal (PNH);   Hodgkin Lymphoma;   Lymphoma, Non-Hodgkin (NHL);   Myelodysplastic Syndrome (MDS)Interventions:   Device: CliniMACS;   Procedure: Stem cell transplantation;   Drug: Systemic chemotherapy and antibodiesSponsor:   St. Jude Children's Research HospitalRecruiting - verified August 2009

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Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders

Friday, December 18th, 2009

Conditions:   Allogeneic Stem Cell Transplant;   Leukemia;   Non-Hodgkins;   Lymphoblastic Lymphoma;   Myelodysplastic Syndrome;   Paroxysmal Nocturnal Hemoglobinuria (PNH)Interventions:   Drug: cytoreductive regimen followed by a CD34+E- selected allogeneic stem cell transplant;   Drug: cytoreductive regimen followed by a CD34+E- selected allogeneic stem cell transplantSponsor:   Memorial Sloan-Kettering Cancer CenterActive, not recruiting - verified May 2009

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Autologous or Syngeneic Stem Cell Transplant Followed by Donor Stem Cell Transplant and Bortezomib in Treating Patients With Newly Diagnosed High-Risk, Relapsed, or Refractory Multiple Myeloma

Friday, December 18th, 2009

Conditions:   Graft Versus Host Disease;   Multiple Myeloma and Plasma Cell NeoplasmInterventions:   Drug: bortezomib;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: melphalan;   Drug: mycophenolate mofetil;   Genetic: fluorescence in situ hybridization;   Genetic: polymerase chain reaction;   Other: flow cytometry;   Other: laboratory biomarker analysis;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: syngeneic bone marrow transplantation;   ...

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Azacitidine After Allo Blood And Marrow Transplantation (BMT) for Chronic Myelogenous Leukemia (CML)

Friday, December 18th, 2009

Conditions:   Stem Cell Transplantation;   LeukemiaInterventions:   Drug: Fludarabine;   Drug: Busulfan;   Drug: Thymoglobulin;   Drug: Azacitidine;   Procedure: Stem Cell TransplantSponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)Recruiting - verified December 2009

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Plerixafor and Granulocyte Colony-stimulating Factor (G-CSF) With Busulfan, Fludarabine and Thymoglobulin

Friday, December 18th, 2009

Conditions:   Stem Cell Transplantation;   LeukemiaInterventions:   Drug: Plerixafor;   Drug: Filgrastim;   Drug: Fludarabine;   Drug: Busulfan;   Procedure: Allogeneic blood stem cell transplant;   Drug: ATG (Thymoglobulin)Sponsors:   M.D. Anderson Cancer Center;   GenzymeRecruiting - verified September 2009

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Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies

Friday, December 18th, 2009

Conditions:   Stem Cell Transplantation;   Leukemia;   LymphomaInterventions:   Drug: Thiotepa;   Drug: Clofarabine;   Drug: Busulfan;   Procedure: Allogeneic Stem Cell Transplantation;   Drug: Thymoglobulin (ATG);   Drug: G-CSF (Filgrastim)Sponsor:   M.D. Anderson Cancer CenterRecruiting - verified September 2009

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Submission of Stem Cell Transplant Data to CIBMTR and NMDP

Friday, December 18th, 2009

Conditions:   Autologous Stem Cell Transplantation;   Allogeneic Stem Cell Transplantation;   Solid Tumors;   Blood CancersIntervention:   Sponsor:   National Cancer Institute (NCI)Recruiting - verified November 2009

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